NOTICE: The Taxi stand/drop-off point at the Medical Centre will be closed on November/December 24. Alternative drop-off locations are available at the Medical Centre (after the carpark gantry) or at the Main Lobby of Mount Elizabeth Hospital.

Dr. Lee Shu Yen

Ophthalmology (Eyes)

Credentials MBBS, FRCSEd(Ophth), FAMS
Language English, Mandarin Chinese, Bahasa Melayu, Teochew Dialect, Hokkien Dialect
Info

Dr Lee graduated from the National University of Singapore and completed her training in ophthalmology at the Singapore National Eye Centre. She then underwent fellowship training in Surgical and Medical retina at SNEC as well as at the Lions Eye Institute, Perth, Western Australia. She previously served as the Head of the Surgical Retina department at the Singapore National Eye Centre leading the team that provided the majority of surgical retina coverage in Singapore.

Dr Lee was the first lady ophthalmologist who was elected as President of the Singapore Society of Ophthalmologists in 2013, a position she held for almost 10 years, during which she enabled the set up of the Young Ophthalmologists section and spearheaded the greater involvement of Singapore ophthalmology in the region when she served as a council member with the Asia Pacific Academy of Ophthalmology (APAO) and the ASEAN Ophthalmology Society (AOS). Dr Lee was a member of the executive committee of the College of Ophthalmologists, Academy of Medicine Singapore, with roles as Secretary and then as Vice-President of the College. These culminated in Dr Lee organising the APAO in Singapore in 2017. Dr Lee was additionally appointed to the MOH committee Diabetes Taskforce which was set up to fight Diabetes nationally.

Associated Treatments

She has a special interest in retinal detachment surgery, complications of high myopia, diabetic retinopathy as well as macula surgery. In addition, Dr Lee is a skilled cataract surgeon who is comfortable with the various types of intraocular lens corrections to help patients achieve their desired visual outcomes as well as the surgical skills and experience to manage complex cataract issues including sclera fix IOLs and post cataract surgery complications.

Special Treatments

Vitrectomy for the complications of high myopia such as myopic traction maculopathy, myopic macula hole and detachments

Vitrectomy for complex retinal diseases eg traction retinal detachments (TRD), giant retinal tears (GRT), proliferative vitreoretinopathy (PVR)

Publications

Dr Lee has more than 100 publications in peer reviewed journals. Her areas of research include retinal detachments, complications of high myopia, imaging, gene therapy and age related macula degeneration

Here are a few papers published

 

  1. Retinal surgery eg. Retinal detachments, giant retinal tears
  • Lee SY, Ong SG, Wong DWK, Ang CL. Giant retinal tear management – an Asian experience. Eye. 2009 Mar;23(3):601-5. Epub 2008 Feb 29
  • Quek D, Lee SY, Htoon HM, Ang CL. Pseudophakic retinal detachment in a large Asian tertiary eye centre: a cohort study. Clin Exp Ophthalmol 2012;40:e1-7
  • Wong CW, Wong WL, Yeo IY, Loh BK, Wong EY, Wong DW, Ong SG, Ang CL, Lee SY. Trends and Factors Related to Outcomes for Primary Rhegmatogenous Retinal Detachment Surgery in a Large Asian Teriary Eye Center. Retina. 2013 Oct 28. [Epub ahead of print] PubMed PMID: 24169100
  • Wong CW, Ang M, Tsai A, Phua V, Lee SY. A Prospective Study of Biometric Stability After Scleral Buckling Surgery. Am J Ophthalmol. 2016 May;165:47-53
  • Tsai ASH, Wong CW, Lim L, Yeo I, Wong D, Wong E, Ang CL, Ong SG, Lee SY, Tan G PEDIATRIC RETINAL DETACHMENT IN AN ASIAN POPULATION WITH HIGH PREVALENCE OF MYOPIA: Clinical Characteristics, Surgical Outcomes, and Prognostic Factors. . Retina. 2018 Jul 13. doi: 10.1097/IAE.0000000000002238
  • Ting DSW, Foo VHX, Tan TE, Sie NM, Wong CW, Tsai ASH,Tan GSW, Lim LS, Yeo IYS, Wong DWK, Ong SG, Wong EYM, Ang CL, Lee SY.  25-years Trends and Risk factors related to Surgical Outcomes of Giant Retinal Tear-Rhegmatogenous Retinal Detachments. Sci Rep. 2020 Mar 25;10(1):5474. doi: 10.1038/s41598-020-61592-0
  • Ge JY, Teo ZL, Chee ML, Tham YC, Rim TH, Cheng CY, Wong TY; SNEC Surgical Retina Research Group; Wong EYM, Lee SY, Cheung N. International incidence and temporal trends for rhegmatogenous retinal detachment: A systematic review and meta-analysis. Surv Ophthalmol. 2024 May-Jun;69(3):330-336. doi: 10.1016/j.survophthal.2023.11.005. Epub 2023 Nov 23. PMID: 38000699
  1. Surgery for the complications of high myopia
  • Lim LS, Tsai A, Wong D, Wong E, Yeo I, Loh BK, Ang CL, Ong SG, Lee SY. Prognostic factor analysis of vitrectomy for retinal detachment associated with myopic macular holes. Ophthalmology. 2014 Jan;121(1):305-10. doi: 10.1016/j.ophtha.2013.08.033. Epub 2013 Oct 16. PubMed PMID: 24139155
  • Cheng C, Teo K, Tan CS, Lee SY, Loh BK, Wong E, Wong D, Wong TY, Cheung CM. Myopic Retinoschisis in Asians: Structural Features and Determinants of Visual Acuity and Prognostic Factors for Progression. Retina. 2016 Apr;36(4):717-26
  1. Age related macula degeneration

 

  1. Gene therapy
  • Shen WY, Lee SY, Yeo IYS, Lai CM, Mathur R, Tan DTH, Constable IJ, PE Rakoczy. Predilection of the macular region to high incidence of choroidal neovascularisation after intense laser photocoagulation in the monkey. Archives of Ophthalmology 2004;122:353-360
  • Chooi-May Lai, Wei-Yong Shen, Meliha Brankov, Yvonne K.Y. Lai, Nigel L. Barnett, Shu-Yen Lee, Ian Y.S. Yeo, Ranjana Mathur, Joseph E.S. Ho, Paul Pineda, Amutha Barathi, Chong-Lye Ang, Ian J. Constable and Elizabeth P. Rakoczy. Long-term Evaluation of AAV-Mediated sFlt-1 Gene Therapy for Ocular Neovascularization in Mice and Monkeys. Molecular Therapy 2005;12(4):659-668
  • Teo KYC,Lee SY, Barathi AV, Tun SBB, Tan L, Constable IJ.  Surgical Removal of Internal Limiting Membrane and Layering of AAV Vector on the Retina Under Air Enhances Gene Transfection in a Nonhuman Primate. Invest Ophthalmol Vis Sci. 2018 Jul 2;59(8):3574-3583. doi: 10.1167/iovs.18-24333.

 

  1. Imaging

Tsai ASH, Gan ATL, Ting DSW, Wong CW, Teo KYC, Tan ACS, Lee SY, Wong TY, Tan GSW, Gemmy Cheung CM.  DIABETIC MACULAR ISCHEMIA: Correlation of Retinal Vasculature Changes by Optical Coherence Tomography Angiography and Functional Deficit. Retina. 2020 Nov;40(11):2184-2190. doi: 10.1097/IAE.0000000000002721

Achievements

Dr Lee was the first lady ophthalmologist who was elected as President of the Singapore Society of Ophthalmologists in 2013, a position she held for almost 10 years, during which she enabled the set up of the Young Ophthalmologists section and spearheaded the greater involvement of Singapore ophthalmology in the region when she served as a council member with the Asia Pacific Academy of Ophthalmology (APAO) and the ASEAN Ophthalmology Society (AOS). Dr Lee was a member of the executive committee of the College of Ophthalmologists, Academy of Medicine Singapore, with roles as Secretary and then as Vice-President of the College. These culminated in Dr Lee organising the APAO in Singapore in 2017. Dr Lee was additionally appointed to the MOH committee Diabetes Taskforce which was set up to fight Diabetes nationally.

Associations

College of Ophthalmologists, Academy of Medicine Singapore

Singapore Society of Ophthalmology

Singapore Medical Association

Macula Society

American Academy of Ophthalmology (AAO)

American Society of Retina Specialists (ASRS)

Asia Pacific Vitreoretinal Society (APVRS)

Awards and Honours

SNEC Long Service Award

COVID Awards

National Day Award 2022

APAO Achievement Award

Fellowships and Accreditations

Retina Fellowships at SNEC and Lions Eye Institute