Dr. Peter Eng Hsi Ko

Dr Peter Eng received his medical degree from the National University of Singapore in 1988. He was subsequently admitted as a Member of the Royal College of Physicians (UK) in 1994. He trained as a specialist in endocrinology at the Singapore General Hospital from 1994 to 1997 and was subsequently awarded a HMDP fellowship to train at the Brigham & Women’s Hospital in Boston from 1998-1999. During his training in Boston, he was the winner of the Endocrine Society’s Knoll award in 1999 for outstanding thyroid research. He received his specialist accreditation in endocrinology in 2000 and became a Fellow of the Academy of Medicine, Singapore in the same year. In 2006, he was inducted as a Fellow of the Royal College of Physicians (UK). He served as a Consultant then Senior Consultant in the Singapore General Hospital Department of Endocrinology as well as the Director of the Singapore General Hospital Diabetes Centre till 2006, when he moved to start his own practice in Mt Elizabeth Medical Centre. Dr Eng’s primary subspecialty interests are in diabetes and thyroid disorders. He does thyroid ultrasounds and ultrasound guided fine needle aspirates of thyroid nodules in his clinic. He also treats osteoporosis, pituitary and adrenal disorders, obesity, lipid disorders, testosterone
deficiency & erectile dysfunction.

PUBLICATIONS
1. Koh LKH, Eng PHK, Lim SC, Tan CE, Khoo DHC, Fok ACK.
Abnormal thyroid and adrenocortical function tests results in intensive care patients.

Ann Acad Med, Singapore 1996; 25:808-15.
2. Eng PHK, Tan KEK, Khoo DHC, Tan CE, Lim HS, Lim SC, LKH Koh, Ho SC,Tai ES, Fok ACK.
Aldosterone to renin ratios in the evaluation of primary aldosteronism.
Ann Acad Med, Singapore 1997; 26:762-6.
3. Khoo DHC, Fok ACK, Tan CE, Koh LKH, Lim SC, Eng PHK, Ho SC.
Thyroid stimulating hormone receptor antibody levels in Singaporean patients with
autoimmune thyroid disease.
Ann Acad Med, Singapore 1997;26:435-8.
4. Lim SC, Pillay P, Khoo DHC, Tan CE, Koh LKH, Eng PHK, Ho SC, Fok ACK.
A patient with pleuri-potent pituitary macroadenoma.
The Endocrinologist 1997; vol7 No 3:189-91.
5. Tan KEK, Khoo DHC, Fok ACK, Eng PHK.
Phaeochromocytoma – A study of four interesting cases.
Singapore Med J 1997;38:493-6.
6. Ho SC, Eng PHK, Ding ZP, ACK Fok ZP, Khoo DHC.
Thyroid storm presenting as jaundice and complete heart block.
Ann Acad Med, Singapore 1998; 7:748-51.
7. Shyong TE, Eng PH.
High and non suppressible plasma renin activity in a patient with aldosterone producing
adenoma: pathologic and diagnostic implications.
J Hum Hypertens 1999; 1:75-8.
8. Eng PHK, Tan L, Wong KS, Cheng, Fok ACK, Khoo DHC.
Cushing’s syndrome in a patient with corticotropin-releasing hormone producing
phaeochromocytoma.
Endocrine Practice 1999; 5:84-7.
9. Ho SC, Tai ES, Eng PH, Ramli A, Tan CE, Fok AC.
A study in the relationships between leptin, insulin, and body fat in Asian subjects.
Int J Obes Relat Metab Disord 1999 Mar;23(3):246-52
10. Khoo DHC, Eng PHK, Ho SC, Fok ACK.
Differences in the levels of TSH binding inhibitor immunoglobulin in agoitrous autoimmune
thyroiditis after twelve months of L-thyroxine therapy.
Clinical Endocrinol 1999; 51:73-9.
11. Eng PHK, Cardona GR, Fang SL, Previti M, Carrasco N, Chin WW, Braverman LE.
Escape from the acute Wolff-Chaikoff effect is associated with a decrease in thyroid
sodium/iodide symporter messenger ribonucleic acid and protein.
Endocrinology 1999; 140:3404-10.
12. Khoo DHC, Ho SC, Seah LL, Fong KS, Tai ES, Chee SP, PHK, Aw SE, Fok ACK.
The combination of absent thyroid peroxidase antibodies and high thyroid stimulating
immunoglobulin levels in Graves’ disease identifies a group at markedly increased risk of
ophthalmopathy.
Thyroid 1999; 9:1175-1180.

13. Ho SC, Eng PHK, Fok ACK, Khoo DHC.
Thyroiditis due to the simultaneous occurrence of silent thyroiditis and Graves’ disease.
Thyroid 1999; 9:1127-32.
14. Lim SC, CE Tan SC, TC Aw SC, Khoo DHC, Eng PHK, Ho SC, Tai ES, Fok ACK.
A man with osteoblastic metastasis and hypocalcaemia.
Singapore Med J 2000; 41:74-76.
15. Khoo DH, Eng PH, Ho SC, Tai ES, Morgenthaler NG, Seah LL, Fong KS, Chee SP, Choo CT, Aw
SE.
Graves' ophthalmopathy in the absence of elevated free thyroxine and triiodothyronine
levels: prevalence, natural history, and thyrotropin receptor antibody levels.
Thyroid 2000; 10:1093-100.
16. Eng PHK, Cardona GR, Previti MC, Chin WW, Braverman LE.
Regulation of the sodium iodide symporter by iodide in FRTL-5 cells.
Eur J Endocrinolol 2001; 144:139-144.
17. Yong AML, Tai ES, Wong ZW, Eng PHK, Khoo DHC
Triiodothyronine predominant Graves’ Disease in a South-East Asian population –
prevalence and clinical significance.
J Endocrinol Invest 2001; 24:204-5
18. Yeo CP, Khoo DH, Eng PH, Tan HK, Yo SL, Jacob E.
Prevalence of gestational thyrotoxicosis in Asian women evaluated in the 8th to 14th weeks
of pregnancy: correlations with total and free beta human chorionic gonadotrophin. Clin
Endocrinol 2001; 55:391-8.

BOOK CHAPTER
1. Eng PHK, Braverman LE
Iodine and Graves’ Disease. In Rapoport B, McLahlan SM, eds. Graves’ Disease
pathogenesis and treatment. Massachusetts, Kluwer Academic Publishers, 2000: 235-247.
2. Eng PHK, Ho SC
Clinical Relevance of the Thyroid Sodium/Iodide Symporter. In Braverman
LE eds . Diseases of the Thyroid 2 nd Edition. Humana Press 2003.
3. Eng PHK, Goh SY, Tan HH
Type 1 Diabetes. In Ong YY, Woo KT, Ng HS, Tan P and Tang OH, eds. A Clinical approach to
Medicine. World Scientific (In press)

Academic, Clinical & Research Awards

1. HMDP fellowship award – July 1998-June 1999
2. Knoll Thyroid Research Clinical Fellowship Award (Awarded by the Endocrine Society) – 1999
3. NMRC fellowship award – July 1999-Nov 1999
4. American Thyroid Association Travel Grant Award – 1999
5. National Medical Research Council Grant (NMRC/0434/2000) – 2000
6. Singapore General Hospital Service Quality Award – 2004
7. Singapore Medical Journal Award for Reviewing with Distinction – 2005

Clinical and Academic positions

• Director, Diabetes Centre Singapore General Hospital – Jan 2001 to July 2006
• Senior Consultant Department of Endocrinology, SGH – Nov 2005 to July 2006
• Clinical Lecturer National University of Singapore Scientific Committee positions – Jul 2004 to July 2006
• Chairman – Mt Elizabeth Hospital Annual Scientific Meeting – 2008
• Chairman – Endocrine and Metabolic Society of Singapore Annual Scientific Meeting – 2002
• Chairman – Introductory Course on Molecular Biology for Clinicians – 2002
• Chairman – Singapore General Hospital Endocrine Update – 2000

1. Endocrine and Metabolic Society of Singapore
2. Diabetes Singapore